An anesthetic causes local or general loss of sensation, including pain. Anesthetics achieve this effect by acting on the brain or peripheral nervous system to suppress the response to sensory stimulation. The non-responsive state caused in this way is called anesthesia. Local anesthesia involves loss of sensation in one area of the body due to blockage of conduction in the nerves. General anesthetics cause anesthesia throughout the body and can be administered by inhalation or by direct injection into the bloodstream.
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